The Santa Marina Resort & Villas is located on a private peninsula which overlooks both the Mediterranean Sea and the Bay of Ornos. The hotel offers a health club called Clarins' Beauty Center, which does manicures, massages and facials. Onsite there are also two churches, a playground, a private beach and a beach bar and BBQ. There is an outdoor pool and poolside restaurant for swimmers, as well as another onsite restaurant and bar, a fitness center, sauna, Jacuzzi and heliport for helicopter travel. The Santa Marina Resort & Villas is located in Ornos Bay, Mykonos in Greece. It is just three miles from the Mykonos Airport. The hotel also features a free mini-bus or private limo service.

Rooms at the Santa Marina Resort & Villas are luxuriously decorated and feature air conditioning, private balconies, bathroom phones, mini bars and safes.

The Santa Marina Resort & Villas consists of 20 acres of property and is listed as a four-star hotel. The architecture is designed to be traditional Cycladic and features 90 guestrooms.